Clinical study on effect of moxibustion on serum apolipoprotein in the old man was made. Results showed that after moxibustion serum apolipoprotein had obvious change with very significant increase of APOAI content as compared with pre- moxibustion.This is of an important significance for regulation of lipid metabolism in the old man, prevention of seline blood lipid increase and arteriosclerosis,coronary heart disease and other angiocardiopathy and cerebrovascular diseases,and delaying senility.