To evaluate the changes of regional cerebral blood flow (rCBF) in panic disorder (PD). Methods: Single photon emmission computed tomography(SPECT) was performed in 16 cases of PD and 15 normal volunteers. Results: Comapared with normal group, panic patients showed significantly decreased rCBF in the following regions; bilateral inferior frontal and temporal cortices, right occipital cortex and left basal ganglia. Regional perfusion indices of patients were negatively correlated with the scores of Hamilton a...