Objective: To observe the effects of osthol and icariin on serum thyroid hormone in mice of kidneyyang insufficiency. Methods: The mice model of hypothyroidism type kidenyyang insufficiency was induced by propylthiouracili (PTU). Osthol and icariin were administered orally to the model mice, and the serum contents of T3, rT3 and T4 were determined by the method of RIA. Results: As compared with that of normal mice, the serum contents of T3, rT3 and T4 in model mice lowered (...