The relationship of fertilizer application rates and flue-cured tobaccoyield was studied by using″416-A optimized regression design″ method The resultsshowed that the fertilizer application rate for high yield is similer with that for high eco-nomic benefitThe practical fertilizer application rates for obtaining 3000kg/ha tobaccoyield are N:2.3~2.6kg,P2O5:18.7~21.7kg,K2O:18.7~23.6kg,been cake(pureN)3.1~4.2kg.The comprehensive effect of all kinds of fertilizers on tobacco yieldsliowed that nitrogen has the g...