β-sitosterol-β-D-glucoside andits aglycone (the major constituent of theseed oil of Hippophae rhamnoides L.)wereinvestigated for their antigastroulcerativeactivity in rats. Two experimental gastriculcer models were selected:chronic aceticacid-induced ulcers and coldstress-inducedulcers. Both the glucoside and its aglyconeshowed antiulcerative activity in chronicacetic acid-induced gastric ulcer models,and their effects were at least comparableto the effects of wishupin in combinationwith cimetidine. The eff...