Anticarcinogenic Activity of Chinese Green Tea Ⅱ.In Vitro Experiment on the Anticarcinogenic Activity and Immune Stimulation with the Extract of Chinese Green Tea
龙雾茶提取物对荷瘤小鼠艾氏腹水癌、肝癌、肉瘤180等实体瘤,以每公斤体重50毫克剂量给药为最佳,抑瘤率分别为45%、57%和61%;艾氏腹水型荷瘤小鼠生命延长率为128%。免疫实验证明,茶叶提取物对小鼠因荷瘤而导致的 T 淋巴细胞和自然杀伤细胞免疫活性反应下降具有显著的回升作用,T 淋巴细胞~(125)IUDR 参入值(cpm)由对照组的932±27提高到2998±210,自然杀伤细胞活性由对照组10.7%提高到41%,恢复到了正常实验小鼠的水平。
【英文摘要】
The dynamic Changes of cellular immune function and anticancer effectof T-8750(an extract of Chinese green tea)in the BALB/C mice bearingEAC,HAH,and S_(180)tumor were investigated.Results showed that intraperitoneal injection T-8750 daily dose 50mg/kg inhibited the EAC,HAH andS_(180)tumor growth about 45%,51% and 61% respectively and the life span ofT-8750 mice bearing EAC ascites tumor prolongad 128%.Daily dose of T-875080mg/kg stimulated the proliferation of T-Lymphocyte S_(180)tumor bearingmice.The ~(126...