The effects of borneoland isoborneol on toxicity, local irrilation,tolerance to lack oxygen, analgesia andthe sleeping time induced by pentobarbitalsodium were compared in mice and rabbits. The oral median lethal dose of bor-neol, isoborneol and synthetic borneol were2879, 2269, and 2507 mg/kg. After borneoland isoborneol 2.5 mg/10 g ip in micewith hot plate, the times of licking hindpaw were prolonged significantly. Borneoland isoborneol 2 mg/10 g ip before themice treated with pentobarbital sodium45 mg/kg...
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