Corynebacterium crenatum SYA 5 is an aerobic, Gram-positive, non-sporulating coryneform bacterium and the mutant C. crenatum strain SYPA 5-5 could produce more L-arginine than its WT strain SYA 5. Strategies for developing amino acid producers are now in transition towards systems metabolic engineering from random mutagenesis. Recently, several amino acid producers have been successfully developed by systems metabolic engineering. There are some efficient strategies and elevations to improve the L-arginine ...