Magnetite nanoparticle (MNP) is an important member of nano material field. MNP shows remarkable functional performances, including superparamagnetic, magnetic responsibility, magnetic induced heating as well as possibility of transport through the vascular system. These properties make MNP widely used in the field of drug target delivery system, hyperthermia, magnetic resonance imaging and purification. However, the synthesis of MNP and multifunctional MNP (such as water-soluble, high biocompatible and flu...