Objectives:
1. To observe the effect on cognitive function of the mental retardated children by acupuncturing Chang qiang point and to research the clinical significance of selecting the point from a distance to treat the disease.
2. The study of expression of upstream activator BDNF、ERK1/2, downstream microtubule associated protein 1B and synaptophysin illustrates the mechanisms of plasticity on Fmrl knocking out mice synapse by puncturing, and provides theoretical basis for mechanisms of modifying...