Investigationon the compatibility law and effective substance of Herb-pairs (HP, Yaodui or Duiyao in Chinese) is the key to elueidate the combing foundation of Traditional Chinese medicine formulas (TCMFs), and also the key researching area supported projeet by Chinese government. The common methods to study the compatibility law of TCMFs or HP including document theory research, study on separated complex prescription, pharmacological effects, components diversity, components in vivo or pharmacokinetics an...