Objectives: Nano material-mediated gene therapy has become a novel strategy for cancer treatment. Nanoparticles as a drug delivery system will play a big role in gene therapy. Currently gene therapy has been a promising clinical approach for treatments of cancer and genetic diseases. The key step of gene therapy is how to accomplish the gene transfer, which is to introduce the exogenous gene into the cells. Application and development of gene therapy have been restricted for two reasons. One is the potentia...