Lacking of efficient medication, cerebritis caused by herpes simplex virus infection - accounting for 10-20% cases of the overall cerbritis - still has been a vital investigation subject in the CNS virus-infected diseases. Though having been proved an efficient drug for herpes simplex virus, penciclovir (PCV) showed less antivirus effect in the CNS owing to its low concentration in the CNS. As polyoxyethylene castor oil was proved increasing the permeability of blood brain barrier, microemulsions comprised ...