Besides surgery, radiotherapy and chemotherapy, gene therapy is potential to be another way for cancer therapy. It may play an important role in preventing cancer from recurrence and metastasis. However, the main issue remains to be resolved is lack of an efficient targeting gene transfer system. Therefore, it is very urgent to develop an efficient targeting gene delivery vector. Since overexpression of EGFR has been frequently found in a wide spectrum of human tumors of epithelial origin, we have attempted...
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