Objective: China is a high-incidence country of esophageal squmous cancer(ESC), more than 50% of all esophageal cancer patients in the world are Chinese, the five-year survival rate of this disease on the whole was less than 10%, the human being are threatened by ESC greatly. So ESC is the disease to be controlled and prevented in our country mainly. But the authentic factors which caused ESC is still unknown, it is difficult to prevent this disease occurring etiologically, so early diagnosis and treatment ...