Sinisan comes from Treatise on Febrile and Miscellaneous Diseases writed by Zhongjing Zhang in Han Dynasty. It is made up of radix bupleuri, Chinese herbaceous peony, citrus aurantium and Radix liquirtiae. It treats diseases with such syndromes caused by impediment in the functional activities of Qi .It is representative recipe to regulate the functional activities of Qi through development of later medical specialist. It apply to such syndromes caused by impediment in the functional activities ...