Newcastle disease(ND)is a severe respiratory, neurological, or enteric disease and is characterized with a high frequency of death among infected chickens. The study investigated the protection of chickens against the ND by a recombinant DNA vaccine. A plasmid vector encoding NDV F protein, which is required for virus cell fusion and is important for vaccine induced immunity, was used as a model to study how DNA may be modulated by the simultaneous expression of chicken IL-2.
Firstly, cDNA encodi...
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