AIM: To investigate the antioxidative activity of the ethanol and water extracts of Lycium barbarum and their dose-effect relationship. METHODS: The Lycium barbarum extracts were provided by our laboratory. Sprague-Dawley rats were killed and then the livers were harvested to isolate the microsomes by calcium precipitation. The oxidant-scavenging potential of the water and alcohol extracts was measured using the following chemiluminescence systems: CoCl2/EDTA-induced luminol chemiluminescence method and xan...