Objective To study the change of serum Apo A I and lipids metabolism in patients with chronic renal diseases.Methods 72 patients with chronic renal diseases were allocated to three groups according to GFR determined by 99m Tc-DTPA. Patients were divided into Group 1 with GFR lower than 50 ml/min,Group 2 with GFR between 50~100 ml/min,and in Group 3 with GFR higher than 100 ml/min. TG?CHOL?ApoA I?Apo B and HDL-C were determined in all cases.Results Concentration of serum Apo A I in Group 1 (1.07±0.29...