Microwave assisted extraction(MAE) of eel bone oil was studied.The optimum parameters for MAE of eel oil were investigated in detail.Experimental results showed that the MAE efficiency was significantly influenced by the microwave radiation time and the moisture.The optimum MAE conditions for 4 g dry sample are as follows:adding 3 mL water,then adding 30 mL chloroform acetone(volume ratio 2∶1),microwave heating for 9 min.