Objective: To study the extraction and separation of effective composition of Pumpkin Polysaccharide and its glucatonic effect. Methods: Pumpkin (Cucurbiat moschata Puch) was water extracted, alcohol precipitated and separated on the macroporous absorption resin column, sepherose and sephadex A 200 columns. The polysaccharide obtained was colded and dried into white powder. The alloxan diabetic rate was given the polysaccharide powder (3.8g/kg) and xiaoke pills (positire control group) for successive 21...