<正> AIM To establish clone cells with different metastaticpotential for the study of metastesis-related mechanisms.METHODS Cloning procedure was performed on parentalhepetocellular carcinoma (HCC) cell line MHCC97,andbiological characteristics of the target clones selected byin vivo screening were studied.RESULTS Two clones with high (MHCC97-H) and low(MHCC97-L) metastatic potential were isolated from theparent cell line.Compared with MHCC97-L,MHCC97-H hadsmaller cell size (average cell diameter 43μm vs 50 ...
【英文摘要】
AIM To establish clone cells with different metastatic potential for the study of metastesis-related mechanisms. METHODS Cloning procedure was performed on parental hepetocellular carcinoma (HCC) cell line MHCC97,and biological characteristics of the target clones selected by in vivo screening were studied. RESULTS Two clones with high (MHCC97-H) and low (MHCC97-L) metastatic potential were isolated from the parent cell line.Compared with MHCC97-L,MHCC97-H had smaller cell size (average cell diameter 43μm v...
【基金】
Supportod ty the State Key Basic Research Program Grant G1998051211 the Fund for Leading Specialty of Shanghai Metropolitan Bureau of Public Health.
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