This paper studied the interactions between Bacillus amyloliquefaciens and Bacillus licheniformis, Saccharomyces cerevisiae and Pichia yeast in Maotai- flavor liquor fermentation by constructed mixed culture system to understand the role of the function and the relationship of microorganisms in fermentation micro-ecological environment. We also used of functional microbial bacteria, yeast and molds to strengthen the high temperature Daqu, and applied it in Maotai liquor production. The studies is to provide...