海洋来源真菌是海洋天然产物和海洋药物的重要来源。特别是珊瑚来源真菌,作为近年来的研究热点之一,越来越引起天然产物及药物研究者的注意。已报道的珊瑚来源的真菌次级代谢产物已经有一百多个,涉及生物碱、大环内酯、萜类、醌类和苯衍生物等结构类型,这些化合物表现出抗藤壶附着、抗菌和细胞毒等生物活性。本课题组已从中国南海软珊瑚Sarcophyton sp来源的一株拟盘多毛孢属真菌Pestalotiopsis sp. (ZJ-2009-7-6)中分离鉴定了3个结构新颖的混源氯代二苯甲酮化合物,包括对映异构体(±)-pestalachlorides C-D和阻转异构体pestalachloride A。在前期工作的基础上,本论文继续对真菌Pestalotiopsis sp. (ZJ-2009-7-6)进行研究,利用海洋天然产物研究方法和现代波谱技术,从中分离鉴定了8个氯代二苯甲酮类化合物,分别为pestalachloride E (1a/b), pestalachloride F (2a/b), pestalalactone (3a/b), (+)-pestalachloride D ((+)-4), (-)-pestalac...
【英文摘要】
Marine-derived fungi have become the most important bioresources for screening and discovery of marine natural products and marine drugs. Especially, coral-derived fungi are increasingly attracting attention of natural products and pharmaceutical researchers as one of the research hotspots in recent years. A literature search revealed that more than 100 compounds were reported from coral-derived fungi. Metabolites from coral-derived fungi mainly contain alkaloids, macrolides, terpenoids, quinones, and benze...
| 
点击下列相关研究机构和相关文献作者，可以直接查到这些机构和作者被《中国知识资源总库》收录的其它文献，使您全面了解该机构和该作者的研究动态和历史。
