Analyzing the Relative Expression of Proteins Which Detected from the Ligament of Hip Joint of Ankylosing Spondylitis by Label-free Quantitative Technique
Ankylosing spondylitis (AS) is autoimmune disease characterized by chronic inflammation and abnormal ossification. At present, peripheral blood and synovial was the most common tissue in the research of AS because of the lesion tissue was hard to get and the knowledge on the pathogenesis of AS was rather limited. HPLC-MS/MS and label-free quantitation technology was used to analysis the proteomics of lesions from hip joint ligament.3 AS and 3 control samples were selected to study the pathogenesis of AS, es...