ObjectivePrevious work demonstratesd that overexpression of Rap2 B was generated in lung cacer tissues.Its overexpression can active NF-κB pathway as well as p38 mitogen-activated protein kinase. The purpose of this study was to detect the expression of NF-κB and p38 in the level of m RNA and protein, the colony forming efficiency, the ability of proliferation and migtation, as well as the assay of cell cycle and apoptosis to explore the role of Rap2 B in lung cancer by RNA interference. This study aims to ...
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