Squid ink melanin is an irregular polymer consisting of an indole structure, which can chelate many kinds of metal ions. Squid ink melanin-Fe is prepared by its compexation properties of melanin. In this study, high-purity squid ink melanin was ertracted from squid ink sac. This paper made a comprehensive assessment of the safety of squid ink melanin-Fe by acute toxicity, genetic toxicity and30-days-feeding test. This paper was to explore ameliorative effect and mechanism of squid ink melanin-Fe on iron def...