Objective: To investigate the modulatory effect of water soluble ingredients ofArnebia euchroma (Royal) Johnston (W-AE) on the immune function ofimmunosuppressed mice. Methods: KM mice were randomly divided into six groups asfollow: Normal control groups (NG, with distilled water), modal (MD, with distilledwater), positive control groups (PG,4.5mg/kg with lentinus edodes mycelia polysacharidetablets), low-dosage groups (LG,1.8mg/kg with W-AE), middle-dosage groups (MG,2.6mg/kg) and high-dosage groups (HG,3....