Brucellosis, which is caused by Brucella, is one of the most important bacterialzoonosis endemic in many countries, especially in developing countries. In2000years,all data suggest that worldwide economic losses due to brucellosis are extensive notonly in animal production but also in public health.
The most critical problem that controlling and eradicating brucellosis in animalsand human beings is that the investigation in its pathogenic mechanism is not fullyclear. Brucella spp. are not found as a fre...