Aim To observe antiatherogenic effects of niacin in hypercholesterolemic rabbits.To explore the effects of niacin on expression of LPL and ABCA1 in the aorta of hypercholesterolemic rabbits and its possible antiatherogenic mechanisms.
Methods Ten male New Zealand white rabbits were fed with 1% cholesterol, 7.5% protein, 8% lard diet for 8 weeks, and then were randomly divided into two groups:(l) starch group: maintained cholesterol diet and starch for 6 weeks.(2) niacin group: the same c...