D-hydroxyphenylglycine(D-pHPG) was the most important precursor used for the synthesis of Semisynthetic penicillin and cephalospor and was a produce competed furiously in the field of pharmacy.Making D-pHPG,enzyme method was better than chemical method which was poisonous.In enzyme method, P-hydroxyphenyldantoin (p-HPH) was transformed into N-Carbamoyl-D-P-hydroxyphenyldantoin(NC-D-pHPG) by Dhydantoinase(DHase), then NC-D-pHPG was transformed into D-pHPG by Ncarbamyl Danimo-acidamidohydrolase (DCase). But n...
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