Objective: To investigate the effects of thyroid hormone on regeneration of mature rat Leydig cells by observing the regeneration of Leydig cells after ethane dimethane sulphonate (EDS) treatment with NBT method, HE staining and magnetic enzyme immunoassay method under hyperthyroidism and hypothyroidism condition.
Methods: Fifty-four 90 day-old male SD rats were applied in this study and EDS (85mg/kg) was injected intraperitoneally only once to destroy Leydig cells. After EDS treatm...