In bacteria, fungi, algae, apicomplexan parasites and plants, there is the shikimate pathway, of which the 5-enolpyruvylshikimate-3-phosphate svnthase (EPSPs) catalyses the conversion of phosphoenolpyruvate (PEP) and shikimate-3- phosaphate (S3P) into5-enolpyruvylshikimate-3-phosphate (EPSP) during the sixth step. Therefore, EPSPs is very significant in bacteria, fungi, algae, and apicomplexan parasitesand plants.According to the unpublished data of our la...