cdc5 gene is necessary for the G2/M transition. Cells with mutations in cdc5 can not finish the G2/M transition, then die; Overexpression of CDC5 can shorten G2, the cell cycle as well. It also makes cells lessening. It was proved that cdc5 gene works in the processes of transcription,cell cycle and splicing of pre-mRNA. And CDCS can transact with other factors, such as NIPP, PRL, IL-2, FGF-2 and DLK.
In the past, We cloned the cDNA of Zmcdc5 based on the studies on difference of gene...
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