Recently, research on using several nucleus metal ion complexes as nucleic acid - cleavage reagents has gotten rapid development on condition, time, efficiency, sequence specificity during the cleavage reaction, whose important reason is that people slowly realize that in according to the structures that the active position of a number of natural enzymes in relation to nucleic acid has two or three cooperative metal ions ,for example Zn(II),Mg(II),Mn(II),Ni(II), Fe(III) etc. Meanwhile, research ...