Objective: To establish a better rat model of H.pylori-associated chronic gastritis .
Methods: One hundred and twenty two-grade male Wister rats were randomly divided into four groups : model group (H.pylori and MNNG group)(80 rats),control groups I (normal control group) (20 rats) , control group II (H.pylori group)( 10 rats) and control group III (MNNG group)( 10 rats) .The model was induced by H.pylori and N-methyl -N' - nitro-N - nitrosoguanidine (MNNG) . H.pylori plan...