Objective: Panic disorder (PD) is one of the most common and importantanxiety disorders in the general hospital. PD is characterized by recurrent, suddenonset, unpredictable and intense horror experience. The mechanism of PD has not yet been fully clarified, and there was a lack of objective biological indicator.The fearful experience of panic attacks is the main clinical manifestations of patients with panic disorder. However, the main theoretical hypotheses on the PD focus on cognitive bias and cognitive ...