Background: Continuous blood purification (CBP) is one of the important progress in the treatment of severe acute renal failure and multiple organ dysfunction syndrome (MODS) in critical illness in recent years. Patients with critical illness is often accompanied with various degrees of bleeding tendency, but the role of heparin anticoagulation is one of the most important reasons caused systemic bleeding complications. CBP anticoagulation has become the bottleneck of CBP technology in clinical appl...
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