The restraint water-immersion stress (RWIS) rat model is widely used to study the stress-induced gastric ulcer and to find the medicine that can cure this disease.The results of many experiments indicated that the RWIS -induced gastric ulcer was mostly due to the parasympathetic hyperactivity that control the stomach while other stresses induced the enhancement of hypothalamo- pituitary- adrenocortical axis (HPA axis) and sympathetic- adrenomedullar(SA). Parasympathetic nerve innervating the stomach...