Object:
To approach the therapeutical effect of L.acdophilus CMS-H002 on acute ulcerative colitis(UC)model,and study the expression variance of TLR4、NF-κBp65、MCP-1 in mice colonic tissue,as well as provide experiment foundation for the therapy of Lactobacillus acidophilus on UC.
Methods:
1.Establish mice acute UC model:
Colitis was induced by exposing BALB/c mice to 2.5%DSS(MW: 50000)in drinking water for 7 days.
2.Investigate the effect of L.acdophilus CMS-H002 strain on acu...