Objective To assess the correlation between abnormal metabolic changes and Wisconsin card sorted test(WCST) in patients with depression using magnetic resonance spectroscopy(MRS).Methods Twelve healthy volunteers(group 1),12 first-episode patients(group 2) and 10 recurrent patients(group 3) underwent WCST before MR examination.Localized magnetic resonance spectra were acquired in bilateral prefrontal lobe and cingulated cortex with single voxel 1-hydrogen MRS(1H-MRS).The ratio of all metabolte including N-a...