[Objective] To observe the effect ele-acupuncture on serum E2 and bone density of rats with osteoporosis.[Method] Make rats model,randomly divide them into model control group(1),ele-acupuncture group(2) and medicinal group(3),with corresponding therapy respectively,then observe index S-E2,lumbar L1-L4 and right thighbone BMD.[Result] Group 2 had higher BMD of S-E2 and lumbar L1-L4 than other two,with right thighbone BMD rising a little,but without marked difference.[Conclusion] Ele-acupuncture can effectiv...