The interactions between fluoroquinolones(sparfloxacin,lomefloxacin,norfloxacin,levofloxacin,fleroxacin and pefloxacin)and bovine serum albumin were investigated by affinity capillary electrophoresis and fluorescence quenching method.The binding molar ratio was 1∶1 and the values of binding constants were all at the magnitude level of 104 L/mol.Both van der Waals interaction and hydrogen bonds were involved in the binding process of these fluoroquinolones to BSA.The ACE results also reveal that with the inc...
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