Ganoderma has been treated as Chinese medicinal and edible fungi since the earliest time, ganoderma lucidum has been widely consumed not only for edible value, but also for its demonstrated efficacy as a popular remedy to treat hepatopathy, hypertension, hyperlipemia, gastric ulcer, leukopenia, nephritis, anticancer. This paper has optimized the process of submerged fermentation of ganoderma lucidum (G4), analysed the medicinal compositions from fruit bodies and mycelia of ganoderma lucidum, explored new me...