Objective: To investigate into the inhibition and mechanism of TSK on nonenzymatic glycation in renal tissue of diabetic rats. Methods: The rats were randomly divided into 4 groups: normal control group(NC group, n=10), Diabetic group(DM group, n=8) , benazepril treated diabetic group(DTl group, n=9), TSK treated diabetic group(DT2 group, u=10). Body weight, Kidney weight and kidney weight / body weight , as well as blood glucose, serum insulin, 24 hours urinary protein excretion, Creatinine clearance were ...