The reevaluation of the animal model of irritable bowel syndrome which combined chronic unpredicted mild stress with acute restrain stress
Background and aims: Irritable Bowel Syndrome (IBS) is a common functional bowel disease. Its etiology and pathophysiology are incompletely understood. Concurrent psychiatric morbidity is prevalent in IBS patients. Psychological stress is known to evoke or exaggerate its symptoms of IBS. The disorder of colonic motility, sensation, mucosal secretion ...
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