Research on ICC Characteristic of Gastric Movement Obstruction Caused by Spleen Deficiency Syndrome and Treated by Chinese Medicine of Strengthening the Spleen
目的
本研究以胃运动起搏细胞—Cajal间质细胞(Interstitial Cell of Cajal,ICC)为主要切入点,从ICC形态与功能、胃电活动、胃排空活动等不同层次探讨脾虚证胃力动障碍的部分发病机制,并为健脾理气代表方香砂六君子汤治疗本病证提供科学的临床与实验依据。
方法
文献研究
部分回顾了20年来国内外学者对脾虚证胃肠运动障碍的认识,综述了胃肠运动研究方法、Cajal间质细胞与胃肠动力障碍疾病及其中医药防治和脾虚证胃肠运动障碍及调控机制研究现状,展望了未来研究新的方法和方向。
临床研究
对60例西医诊断为慢性胃炎伴有胃肠运动障碍的脾虚证患者用传统的以症状、舌象、脉象进行中医辨证定型,将符合纳入标准的患者随机分为中药治疗组和西药治疗组,另外选择正常人10例作胃排空、胃电图对照组。中药治疗组用香砂六君子汤(组成和用量参照《方剂学》教材):白术15g,甘草10g,制半夏15g,党参15g,陈皮10g,茯苓15g,木香10g(后下),砂仁10g(后下),每日一...
【英文摘要】
ObjectiveThe research made gastric movement' s pacemaking cell and Interstitial Cell of Cajal (ICC) as the incision, probed into the pathological mechanism of gastric movement obstruction caused by spleen deficiency syndrome from the form and function of ICC, electricgastro- movement, the gastric emptying movement. It also can provide clinical and experimental proof for XiangSha Six Mild-Drug Decoction to treat spleen deficiency syndrome. Method The section of documentary research:Reviewed partly the unders...