【摘要】 目的:观察冷循环射频消融治疗肝肿瘤的近期疗效。方法:运用HG-3000型单针冷极射频肿瘤治疗机对43例肝癌患者总计117个瘤体进行消融治疗。运用CT及B超观察瘤体的变化,测定AFP、CEA、肝功能,并与治疗前进行比较。结果:117个瘤体的生长均受到明显抑制,AFP值较治疗前明显下降(P<0.05);CEA值呈持续升高趋势,治疗后第3、4、5月CEA值与治疗前比较有明显差异(P<0.05);肝功能在治疗后1、2周变化较为明显,4、5周后恢复治疗前水平。结论:冷循环射频消融治疗肝肿瘤近期疗效满意,并发症少。更多还原

【Abstract】 Objective:To observe the short-term curative effect of radiofrequency ablation with active electrode cooling in the treatment of hepatocarcinoma.Methods:Radiofrequency ablation therapy was targeted to 117 tumor bodies of 43 patients with hepatocarcinoma using cooled-tip radiofrequency energy delivery machine(HG-3000).The change of tumor size was observed using CT and type B ultrasonic examination.The level of alpha-fetoprotein(AFP),carcinoembryonic antigen(CEA),the liver function were recorded and compared with pretreatment.Results:Radiofrequency ablation therapy significantly inhibited the growth of 117 tumor bodies.The AFP value obviously decreased compared with pretreatment(P<0.05);the CEA value had the tendency to continually increase.The CEA value had significant difference after 3-,4-,and 5-month therapy compared with pretreatment(P<0.05).The liver function had obvious changes after 1-or 2-week therapy and recovered to the primary value before treatment after 4 to 5 weeks.Conclusion:The radiofrequency ablation with active electrode cooling may achieve satisfactory efficacy and has little complications.更多还原