【摘要】 目的:探讨经阴道彩色多普勒超声对卵巢良、恶性肿瘤的诊断价值及其与临床分期的关系。材料和方法:对47例卵巢恶性肿瘤,18例良性肿瘤,5例交界性肿瘤患者术前行经阴道彩色多普勒超声检查。分析瘤内血管分布类型、瘤内动脉血流参数及动脉频谱舒张期切迹等指标与良、恶性肿瘤及临床分期的关系。结果:卵巢恶性肿瘤动脉血流RI值明显低于良性组,且Ⅲ、Ⅳ期RI值明显低于Ⅰ、Ⅱ期。恶性组血管分布多为Ⅲ型,占38/47,良性组血管分布Ⅲ型为1/18,以血管分布Ⅲ型为标准诊断卵巢恶性肿瘤敏感性80.8%,特异性86.9%。恶性组4/47动脉频谱有舒张期切迹,良性组14/18动脉频谱有舒张期切迹,两组比较差异有统计学意义。结论:RI、血管分布类型、脉冲频谱舒张期切迹是鉴别卵巢良、恶性肿瘤的重要指标,对评价预后有一定的参考价值。更多还原

【Abstract】 Purpose: The aims of this study were to explore the value of transvaginal color Doppler ultrasonography(TVCDU)in diagnosing ovarian tumors and to analyze the relationship between tumor blood supply and its clinical stages. Materials and Methods: 47ovarian carcinomas, 5 borderline tumors and 18 benign tumors were examined preoperatively with TVCDU. The vascular indices(PSV、EDV、RI), vascularity pattern(VP), diastolic notch(DN)were recorded. Those indices(PSV, EDV, RI, VP and DN) were analyzed in an attempt to differentiate benign and malignant ovarian tumors. The relation between RI and clinical stage of the tumors was also investigated. Results:RI in ovarian carcinomas was lower than that in benign tumors. Using RI ≤0.5 as a diagnostic threshold, the sensitivity and specificity in detecting ovarian carcinomas were 85.1% and 78.3% respectively. RI in stage Ⅲ and Ⅳ were lower than that in stageⅠand Ⅱ. 38/47(81%) malignant ovarian tumors were of hyper-vascularity, significantly different with benign ones(1 /18, 5.6%). Using hyper-vascularity as a standard, the sensitivity and specificity were 80.8% and 86.9% respectively. The diastolic notch was much less encountered in malignant tumors(4/47, 8.5%) than benign (14/18, 77.8%). Conclusion: TVCDU was an effective method for differentiation of malignant from benign ovarian tumors, and for clinical staging and prognosis.更多还原