【摘要】 目的为早期正确诊断KD提供临床依据。方法对2005年1月~12月住院KD患儿107例进行研究,分析各种不典型病例的特点和临床表现的发生率。结果①107例KD不典型病例占19.6%,≤3岁的病例占62.6%;②不典型病例确诊较晚,冠脉损害发生率与典型病例相仿;③典型临床表现中淋巴结肿大(直径≥1.5 cm)的发生率最低,仅占24.3%,肢端硬肿的发生率次之(48.6%);④烦躁易激惹、卡瘢再现红斑、肛周脱皮在发病早期出现率分别为94.4%,35.5%,51.4%;ESR快(≥40mm/h)67.3%,CRP高(≥30 mg/L)50.5%。结论将常见临床特点、实验室检查纳入诊断标准可能有利于临床医生早期诊断KD。更多还原

【Abstract】 Objective:The aim of this analysis is to provide clinical evidence for the earlier diagnosis of Kawasaki disease(KD).Methods: Totally 107 patients with KD were hospitalized from Jan.to Dec.2005,which clinical features were analyzed.Results: ①Among the 107 KD patients,21(19.6%) were diagnosed as atypical KD(AKD).Most of them(62.6%) were younger than 3 years old.②AKD were diagnosed later than typical cases,and cardiac compliance is similar between them.③Cervical lymph node changes(24.3%) were the least commonly seen diagnostic feature,followed by the extremity oedema(48.6%).④Irritability(94.4%),erythema and induration at sites of BCG immunizations(35.5%) and desquamation around anus(51.4%) were noted.67.3 percent cases had erythrocyte sedimentation rate(ESR) above 40 mm/h,50.5 percent had C reactive protein (CRP) more than 30mg/L.Conclusion: Some common clinical features which were not included in the KD diagnosis criteria and supplementary laboratory test may be useful in the earlier diagnosis of KD.更多还原